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Senior Software Developer

Guidehouse Open
Remote Any location Full-time Senior Software Engineering

At a glance

Senior Software Engineering role at Guidehouse. Remote, United States · full-time · $113,000–$188,000 base.

SalaryStated by Guidehouse
$113,000 – $188,000
Base salary for this role, in USD per year, as published in the posting.
This role, from GuidehouseOur estimate for the market: $155,725–$174,613Median $166,500
The range includes the market median of $166,500 for senior software engineering roles in Any location, compared against the Any location market.
Worked out from 6 postings that stated pay, median $166,500. Last updated Oct 23, 2026.
RoleSoftware Engineering
SenioritySenior
LocationAny location
WorkplaceRemote
EmploymentFull-time
Base pay$113,000–$188,000
PostedApr 27, 2026
Role brief

remoteroles summary, based on the employer's posting.

What you'll do

  • Build and maintain web and mobile applications, adding features that fit existing codebases
  • Create APIs, data pipelines and computational services, and improve analysis pipelines as datasets grow
  • Develop reusable React interfaces that help researchers and clinicians work with scientific data and workflows
  • Test and document code, track work, review security findings, and help deploy and maintain software
  • Work with scientists, clinical staff and technical teams to shape workflows, share feedback and mentor developers

What you bring

  • A master's degree in computer science or a related area
  • At least six years developing and maintaining full-stack web applications with Python and React
  • At least three years working with databases, plus experience deploying software on AWS and building Docker containers
  • Experience with GitHub Actions, REST services, and deployments across multiple environments, including reviewing teammates’ code
  • You can obtain and maintain Public Trust clearance and explain technical concepts clearly to non-computational users

Who this fits

This remote or on-site role suits a senior full-stack developer comfortable working with researchers, clinicians and nontechnical experts. Periodic in-person attendance is required in Tysons Corner, Virginia, and Rockville, Maryland; travel may reach ten percent. Public Trust adjudication must be approved before onboarding.

From the employer

Job Family:

Software Development & Support


Travel Required:

Up to 10%


Clearance Required:

Ability to Obtain Public Trust

We are seeking a highly skilled, dynamic developer with full stack expertise using Python and JavaScript technologies. The developer will support web and mobile applications used by researchers and clinicians at the National Institute of Allergy and Infectious Diseases (NIAID) in the National Institutes of Health (NIH). This opportunity is a full-time position with Guidehouse and can be remote or on-site at NIH in Rockville, MD. Periodic onsite presence is required, including in‑person new‑joiner orientation in Tysons Corner, VA and occasional onsite team meetings in Rockville, MD.

The Senior Software Developer will collaborate closely with PhD-level scientists and subject matter experts to translate complex scientific workflows into reliable, scalable services and to design user interfaces that make complex scientific data and workflows accessible and actionable. Responsibilities include designing and implementing APIs, data processing pipelines, and computational services, developing reusable React components, integrating with APIs, ensuring performance and usability at scale, contributing to system architecture, writing well-tested, maintainable code, and mentoring other developers. Experience with scientific computing libraries, data-intensive workloads, or distributed systems is highly desirable. Applications developed by the team are used in clinical and research settings and development is driven by continued use and iterative feedback from researchers and clinical staff as well as subject matter experts and software development team members. Strong communication skills for this position are essential as the Developer may need to frequently converse with non-computational subject matter experts.

What You Will Do:

The role will be responsible for creating and maintaining applications and will entail:

  • Participate in a highly integrated software development team working in an agile environment, documenting code, testing code, and tracking tasks

  • Develop new applications as well as extend existing applications; develop new features and customizations that harmonize with existing codebases

  • Find creative solutions to scale the performance of existing analysis pipelines to meet the demands of rapidly growing datasets

  • Collaborate between the project team and internal teams to support enterprise infrastructure to deploy and maintain software

  • Experiment with new technologies and systems as well as prototype solutions for potential integration into existing infrastructure

  • Review and address security vulnerabilities in collaboration with our security and infrastructure teams


What You Will Need:

M.S. in computer science or related field

Key technologies: React, TypeScript/JavaScript, Python, Docker, AWS (e.g., ECS/EKS, S3, RDS), CI/CD pipelines with GitHub Actions

Experience/Skills

  • Minimum Six (6) years of Full stack web application development and maintenance experience, including development in Python and React

  • Minimum Three (3+) years of experience working with databases

  • Experience building containerized applications using Docker

  • Experience using GitHub actions

  • Minimum Two (2+) years of experience with Git and code deployments to multiple environments and involving reviewing the contributions of multiple team members

  • Experience deploying and operating software on AWS

  • Experience mentoring other developers and reviewing and providing feedback on other developer’s work

  • Experience developing and using RESTful web services and JSON or XML objects for communication

  • Experience communicating with end users on software development projects; being comfortable explaining complex computational terms using simple language for a non-computational audience

  • Demonstrated experience extending the functionality of existing software; ability to learn an existing body of code and extend it

  • Ability to meet position requirements that include required in‑person activities, such as new‑joiner orientation in Tysons Corner, VA and onsite meetings in Rockville, MD, as determined by program and business needs.

  • Must be able to obtain and maintain a Federal or DoD Public Trust. Candidates must receive approved adjudication of their Public Trust prior to onboarding with Guidehouse. Candidates with an active Public Trust or existing suitability are preferred.


What Would Be Nice To Have:

  • Knowledge of terraform

  • Familiarity with SCRUM/Agile development

  • Familiarity with Swagger/O

  • penAPI

  • Experience visualizing complex or large-scale data sets

  • Experience reviewing and responding to security vulnerability reports

  • Background in bioinformatics, genomics, or computational biology

The annual salary range for this position is $113,000.00-$188,000.00. Compensation decisions depend on a wide range of factors, including but not limited to skill sets, experience and training, security clearances, licensure and certifications, and other business and organizational needs.


What We Offer:

Guidehouse offers a comprehensive, total rewards package that includes competitive compensation and a flexible benefits package that reflects our commitment to creating a diverse and supportive workplace.

Benefits include:

  • Medical, Rx, Dental & Vision Insurance

  • Personal and Family Sick Time & Company Paid Holidays

  • Parental Leave

  • 401(k) Retirement Plan

  • Group Term Life and Travel Assistance

  • Voluntary Life and AD&D Insurance

  • Health Savings Account, Health Care & Dependent Care Flexible Spending Accounts

  • Transit and Parking Commuter Benefits

  • Short-Term & Long-Term Disability

  • Tuition Reimbursement, Personal Development, Certifications & Learning Opportunities

  • Employee Referral Program

  • Corporate Sponsored Events & Community Outreach

  • Care.com annual membership

  • Employee Assistance Program

  • Supplemental Benefits via Corestream (Critical Care, Hospital Indemnity, Accident Insurance, Legal Assistance and ID theft protection, etc.)

  • Position may be eligible for a discretionary variable incentive bonus

About Guidehouse

Guidehouse is an Equal Opportunity Employer–Protected Veterans, Individuals with Disabilities or any other basis protected by law, ordinance, or regulation.

Guidehouse will consider for employment qualified applicants with criminal histories in a manner consistent with the requirements of applicable law or ordinance including the Fair Chance Ordinance of Los Angeles and San Francisco.

If you have visited our website for information about employment opportunities, or to apply for a position, and you require an accommodation, please contact Guidehouse Recruiting at 1-571-633-1711 or via email at RecruitingAccommodation@guidehouse.com. All information you provide will be kept confidential and will be used only to the extent required to provide needed reasonable accommodation.

All communication regarding recruitment for a Guidehouse position will be sent from Guidehouse email domains including @guidehouse.com or guidehouse@myworkday.com. Correspondence received by an applicant from any other domain should be considered unauthorized and will not be honored by Guidehouse. Note that Guidehouse will never charge a fee or require a money transfer at any stage of the recruitment process and does not collect fees from educational institutions for participation in a recruitment event. Never provide your banking information to a third party purporting to need that information to proceed in the hiring process.

If any person or organization demands money related to a job opportunity with Guidehouse, please report the matter to Guidehouse’s Ethics Hotline. If you want to check the validity of correspondence you have received, please contact recruiting@guidehouse.com. Guidehouse is not responsible for losses incurred (monetary or otherwise) from an applicant’s dealings with unauthorized third parties.

Guidehouse does not accept unsolicited resumes through or from search firms or staffing agencies. All unsolicited resumes will be considered the property of Guidehouse and Guidehouse will not be obligated to pay a placement fee.

Opportunity

Software Engineering work from LinkedIn, X, Reddit and Upwork, in one list.

Each morning you get everything that fits, strongest first.

Software EngineeringRemote$110k+

Find me work

By the team behind remoteroles.

Find me work
Opportunity

Software Engineering work from LinkedIn, X, Reddit and Upwork, in one list.

Each morning you get everything that fits, strongest first.

Find me work

By the team behind remoteroles.