Senior Director, Clinical Science
Remote United States Full-time Director Other
At a glance
Director-level role at Kyverna Therapeutics. Remote, United States · full-time · $260,000–$290,000 base.
SalaryStated by Kyverna Therapeutics
$260,000 – $290,000
Base salary for this role, in USD per year, as published in the posting.
RoleOther
SeniorityDirector
LocationUnited States
WorkplaceRemote
EmploymentFull-time
Base pay$260,000–$290,000
PostedSep 17, 2026 · 5w ago
Role brief
remoteroles summary, based on the employer's posting.
What you'll do
- Guide CAR T-cell clinical trials for autoimmune indications, working with internal teams and external partners
- Set trial plans and oversee how studies are run, then interpret the results across your assigned program
- Shape development plans and study materials, including protocols, investigator brochures and regulatory submissions
- Lead clinical content for safety updates, study reports and health authority responses with the study physician
- Represent the program with study teams, scientific leaders and partners, while mentoring clinical scientists and staff
What you bring
- An advanced scientific or life sciences degree, such as a Ph.D., Pharm.D. or M.D
- At least ten years in drug development, including work across multiple programs and late-stage global trials
- Required experience in late-stage studies and a strong grasp of global regulatory rules and development pathways
- A record of building and carrying out clinical strategies at the program level
Who this fits
This role suits a senior clinical science leader who can direct program strategy, work independently and develop other scientists. The position is remote or hybrid and may require travel up to fifteen percent of the time. It includes leading, mentoring and developing staff.
From the employer
Kyverna Therapeutics is a patient-centered, clinical-stage biopharmaceutical company developing cell therapies for patients suffering from autoimmune diseases. Guided by our core values, Stay True to Why, Collaborate to Accelerate, Lead with Clarity, Boldly Innovative, and Own the Outcome, we are committed to transforming the future of treatment for autoimmune disease. Join us at the forefront of cell therapy innovation and help redefine what’s possible.
Title: Senior Director, Clinical Science
Location: Remote or Hybrid
Reports To: SVP, Clinical Development & Medical Affairs
Responsibilities
- Serve as the senior clinical scientist for CAR T-cell therapy clinical trials in autoimmune disease indications, in partnership with internal and external cross-functional teams
- Partner with clinical operations, biometrics, regulatory, and commercial teams to ensure alignment on strategy and execution
- Lead design, execution, and interpretation of clinical trials across assigned program
- Provide scientific input into clinical development plans, study protocols, investigator brochures, and regulatory submissions.
- Participate in the development of clinical trial documents including protocols, ICFs, clinical development plans, and publications.
- Lead the development of clinical sections of regulatory documents including the IB, safety updates, clinical study reports, and responses to Health Authorities in collaboration with the study physician.
- Represent Clinical Development for the assigned program with cross-functional leaders
- Represent Clinical Development for the assigned program with key opinion leaders and strategic partners to inform clinical and scientific strategy
- Represent Clinical Development for the study team in high-impact external settings (advisory boards, regulatory meetings, major congresses), as appropriate
- Contribute to external scientific narrative and positioning through publications, presentations, and collaborations.
- Ensure compliance with GCP, corporate policies, and applicable local regulations.
- Lead, mentor, and develop high-performing clinical scientists and other staff
- Foster a culture of innovation, accountability, and scientific rigor.
- Contribute to Clinical Development organizational design and capability building to support future pipeline growth and complexity.
Qualifications
- Advanced degree (Ph.D., Pharm.D., M.D., or equivalent) in a scientific or life sciences discipline required
- 10+ years of progressive experience in drug development, including significant experience across multiple programs, including late-stage global clinical trials
- Demonstrated success in developing and executing clinical strategies at a program level
- Experience in late-stage clinical trials required; experience with BLA/NDA filing preferred
- Experience in cell and gene therapy, immunology, autoimmune disease, or related fields preferred
- Deep understanding of global regulatory frameworks and clinical development pathways required
- Strong operational acumen with excellence and efficiency
- Exceptional communication and management skills
- Ability to operate independently and effectively in a fast-paced, highly dynamic environment
- Ability to travel up to 15% of the time
Other work from LinkedIn, X, Reddit and Upwork, in one list.
Each morning you get everything that fits, strongest first.
OtherRemote$260k+
Find me workBy the team behind remoteroles.